منابع مشابه
Adaptive gene regulatory networks
Regulatory interactions between genes show a large amount of cross-species variability, even when the underlying functions are conserved: there are many ways to achieve the same function. Here we investigate the ability of regulatory networks to reproduce given expression levels within a simple model of gene regulation. We find an exponentially large space of regulatory networks compatible with...
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Fractal proteins are an evolvable method of mapping genotype to phenotype through a developmental process, where genes are expressed into proteins comprised of subsets of the Mandelbrot Set. The resulting network of gene and protein interactions can be designed by evolution to produce specific patterns that in turn can be used to solve problems. In this paper, adaptive developmental programs, c...
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Tryptophan is one of the 20 amino acids that link together to form proteins. For humans it is an essential amino acid, we must get it from our diet since we cannot synthesize it. E. coli bacterial cells, however, can synthesize the amino acid tryptophan when it is not provided from the environment (e.g. the gut where it lives). It would be wasteful to synthesize tryptophan when it is readily av...
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Differential gene expression plays a critical role in the development and physiology of multicellular organisms. At a 'systems level' (e.g. at the level of a tissue, organ or whole organism), this process can be studied using gene regulatory network (GRN) models that capture physical and regulatory interactions between genes and their regulators. In the past years, significant progress has been...
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ژورنال
عنوان ژورنال: EPL (Europhysics Letters)
سال: 2009
ISSN: 0295-5075,1286-4854
DOI: 10.1209/0295-5075/88/48004